Bioactivation of xenobiotics: in vitro toxicology systems; renal/hepatic
toxicology; toxicity of halogenated hydrocarbons, and metals; mechanisms
cell injury.
Wijeweera JB, Gandolfi AJ, Parrish A, Lantz RC. Sodium arsenite
enhances AP-1 and NF6B DNA binding and induces stress protein
expression in precision-cut rat lung slices. Tox Sci, 61:283-294,
2001.
Catania JM, Parrish AR, Gandolfi AJ. Toxicity of a sevoflurane
degradation product incubated with liver and renal cortical slices.
Drug Chem Tox 24:347-357, 2001.
Zheng XH, Begay CK, Lind RC, Gandolfi AJ. Humoral immune response
to a sevoflurane degradation product in the guinea pig following
inhalation exposure. Drug Chem Tox 24:339-346, 2001.
Fisher RL, Gandolfi AJ, Brendel K. Human liver is a dominant
factor in the outcome of in vitro studies. Cell Biol Tox, 17:179-189,
2001.
Parrish AR, Sallam K, Nyman DW, Orozco J, Cress AE, Dalkin BL,
Nagle RB, Gandolfi AJ. Culturing precision-cut human prostate
slices as an in vitro model of prostate pathobiology. Cell Biol
Tox, 18:205-219, 2002.
Fisher RL, Hasal SJ, Lipscomb JC, Gandolfi AJ, Brendel K. Cold-
and cryopreservation of monkey liver slices. Toxicology Mechanisms
Methods, 12:119-133, 2002.
Catania JM, Parrish AR, Kirkpatrick DS, Chitkara M, Bowden GT,
Henderson CJ, Wolf CR, Clark AJ, Brendel K, Fisher RL, Gandolfi,
AJ. Precision-cut tissue slices from transgenic mice as an in
vitro toxicology system. Tox In Vitro, in press, 2002.\
Kirkpatrick DS, Dale KV, Catania JM, Gandolfi AJ. Low-level arsenite
causes accumulation of ubiquinated proteins in rabbit renal cortical
slices and HEK293 cells.
Tox Appl Pharm, submitted, 2002
Zheng XH, Watts G, Vaught S, Gandolfi AJ. Low-level arsenite
induced gene expression in HEK293 cells. Toxicology, submitted,
2002.
Begay CK and Gandolfi AJ. Late administration of COX-2 inhibitors
minimizes hepatic necrosis in chloroform induced liver injury.
Toxicology, in revision, 2002.
