John
W. Bloom, M.D., Associate Professor
Molecular mechanisms of glucocorticoid action in the lung; mechanisms
of eosinophil apoptosis; effects of genetic polymorphisms on gene expression
in asthma.
Qin
M. Chen, Ph.D., Associate Professor
Molecular mechanisms of oxidative injury and adaptation, stress signal
transduction pathways, stress gene expression, senescence, apoptosis and
cardiac hypertrophy.
Thomas
P. Davis, Ph.D., Professor
Neuropharmacology; molecular regulation of growth factor processing
and metabolism; biotech approaches to targeting the blood-brain barrier
for new drug development; effects of hypoxia, aglycemia and nicotine on
endothelial cell permeability, resistance and cytoarchitecture.
Robert
T. Dorr, Ph.D., Professor
Toxicology systems and mechanisms of action of cytotoxic anticancer
agents; the pharmacology of cancer chemopreventive agents.
Gregory
Dussor, Ph.D., Assistant Professor
Mechanisms of pain signaling from the skin & ion channels
involved in pain signaling.
Edward
D. French, Ph.D., Professor
Neuropharmacology of drugs of abuse, addiction, and CNS responses to stressful
stimuli using electrophysiological and behavioral endpoints.
Marilyn
J. Halonen, Ph.D., Professor
Immunopharmacology; cytokine regulation of IgE synthesis; cell biology
of cytokine and receptor differences as a result of naturally occurring
polymorphic genes related to asthma or allergy in the population; immune
responses in infancy to respiratory viruses and allergens and immune alterations
in asthma.
Josephine
Lai, Ph.D., Professor
Molecular mechanisms of neuropathic pain; opioid receptor pharmacology;
gene targeting, drug discovery.
Patrick W. Mantyh, Professor, PhD., JD, University of California, San Francisco, 1981, JD William Mitchell College of Law, 1994, Cancer, cancer pain and non-malignant bone pain, stem cells and skeletal health in disease and aging.
John Palmer, M.D., Ph.D., Professor Emeritus. Cardiovascular and clinical pharmacology; studies of cardiovascular and pulmonary changes associated with acute hypersensitivity responses and systemic anaphylaxis.
Frank
Porreca, Ph.D., Professor
Neurobiology of pain.
Theodore Price, Assistant Professor, Ph.D., University of Texas, 2003. Regulation of activity-dependent protein synthesis in nociceptors and nociceptive projection neurons; control of anion homeostasis in the pain pathway.
I.
Glenn Sipes, Ph.D., Professor and Head
Mechanism of tissue injury induced by drugs or other xenobiotics;
mechanisms by which one chemical modulates the toxicity of another; carcinogenesis,
human metabolism of environmental pollutants.
Robert
S. Sloviter, Ph.D., Professor
Neuropharmacology, neurotoxicology, neuroanatomy, and neurophysiology
of epilepsy and other neurological disorders; mechanisms of neuronal death;
anticonvulsant drug mechanisms.
Todd
W. Vanderah, Ph.D., Associate Professor
Mechanisms and pharmacology of acute and chronic models of pain; endogenous
opioid systems; sensory neural systems; opioid tolerance; antinociceptive
synergy between cannabinoids and opioids.
Henry
I. Yamamura, Ph.D., Regent’s Professor
Neuropharmacology; mechanism of psychotropic drugs in the CNS; molecular
biology of neurotransmitter and drug receptors; second messenger coupling
with receptors.
Affiliate Faculty
Peter B. Chase, M.D., Ph.D., Clinical Emergency Medicine.
Jack H. Dean, Ph.D., Sc.D., DABT, Fellow ATS, Professor, Department of Pharmacology and Toxicology, College of Pharmacy. Research interests include the safety assessment of new pharmaceutical entities, acceleration of the drug development process, immunotoxicology, and models for understanding toxicity at a molecular level.
Ronald P. Hammer, Jr., Ph.D., Professor, Departments of Basic Medical Sciences and Pharmacology - The University of Arizona College of Medicine—Phoenix in partnership with Arizona State University, Professor, Department of Psychology - Arizona State University.
Israel Hanin, Visiting Professor, Professor and Chair Emeritus, Ph.D., Loyola University, Chicago. Alzheimer's and Parkinson's diseases.
Victor Hruby, Regents Professor,Ph.D., Department of Chemistry. The chemistry of human behavior especially peptide hormones and neurotransmitters; drug design, discovery and development; pain, addiction, feeding behavior, sexual behavior, pigmentation disease, cancer, diabetes, immune response; GPCRs; biophysics/biochemistry of health and disease.
David G. Johnson, M.D., Professor, Department of Medicine. Endocrine pharmacology; pharmacology and physiology of pancreatic function; peptide hormones; clinical pharmacology.
Douglas
F. Larson, Ph.D., Professor, Department of Surgery
Immunopharmacology: pharmacology and design of selective immunosuppressive
therapies for solid organ transplantation and auto-immune diseases.
Ronald
Lukas, Ph.D., Professor, Barrow Neurological Institute
Nicotinic acetylcholine receptor biology using clonal lines and transgene
expression systems; neurotrophic factors; neurodegenerative diseases;
neuronal differentiation.
T.
Philip Malan, Jr., M.D., Ph.D., Professor, Department of Anesthesiology
Neuropharmacology; pharmacology and molecular biology of neuropathic
pain.
Robin Polt, Ph.D., Professor of Chemistry. Synthesis and new synthetic methods, drug design and transport. Neuropsychopharmacology and the blood-brain barrier.
William
Roeske, M.D., Professor, Department of Medicine
Cardiovascular pharmacology; regulation, characterization, and identification
of autonomic receptors; neuropharmacology of drugs of abuse.
F. Mazda Shirazi, M.D., Ph.D., Clinical Emergency Medicine.
Daniel
Stamer, Ph.D., Professor, Department of Opthalmology
Molecular and cellular mechanisms that underlie the regulation of
aqueous humor outflow in the human eye; including receptor activation,
second messenger signaling, ion and water transport, and secretory function.
Research Track
Juan Miguel Jimenez Andrade, Assistant Professor, Ph.D.,
Tamara
King, Ph.D., Assistant Professor
Pharmacology; neurochemical signaling of noxious and innocuous sensory
inputs to the spinal cord; mechanisms of chronic morphine induced abnormal
pain.
Ronald Lukas, Ph.D., Professor
Michael
H. Ossipov, Ph.D., Associate Professor
Pharmacology; neurophysiology, pharmacology and neuroanatomical pathways
of acute and chronic pain states; isobolographic and statistical interpretation
of drug-drug interactions.
Sangita Pawar, Ph.D., Assistant Professor
Eva
Varga, Ph.D., Assistant Professor
Molecular pharmacology of drugs of abuse; cellular mechanisms of drug
tolerance; design and characterization of non-addictive analgesics, cardioprotective
agents, and immunomodulators.
George Watts, Ph.D., Assistant Professor
Investigation of esophageal adenocarcinoma, a cancer with a poor prognosis
that arises from a common change in the tissue lining the esophagus referred
to as Barrett's esophagus. Dr. Watts has analyzed the changes in gene
expression that are associated with progression from Barrett's esophagus
to cancer. The genes identified during microarray-based studies are being
developed as biomarkers and targets for improving therapy.
Colin Willis, Ph.D., Assistant Professor
Mechanisms of Glial/endothelial cell/extracellular matrix interactions
at the blood-brain barrier and effect on vascular permeability in acute
and chronic disease states.
Postdoctoral Fellows
Melina De Felice
Tannia Gutierrez
Monica Herrera Hernandez
Robert Kuester
Miaw-Chyi Luo
Shou-Wu Ma
Edita Navratilova
Louis Vera-Portocarrero
Melissa Seelbach
Marina Vardanyan
Bei Bei Xu
Qianli Yu
Dongqin Zhang
Professors Emeriti
Klaus Brendel, Ph.D.
Ryan Huxtable, Ph.D.
John Palmer, M.D., Ph.D.
